RNA Details
Disease Name
hepatitis
Tissue
liver
RNA Symbol
mir-16-1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
enzyme-linked immunosorbent assay; PCR etc.
Target
SMAD7
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Increased miR-16 expression induced by hepatitis C virus infection promotes liver fibrosis through downregulation of hepatocyte growth factor and Smad7
Year
2015
Function
"Hepatitis c virus infection induced mir-16 up-regulation, by down-regulating hepatocyte growth factor and smad7 to promote liver fibrosis."